Biological variation of free plasma amino acids in healthy individuals

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Biological variation of free plasma amino acids in healthy individuals.

BACKGROUND Biological variation data for free plasma amino acids are lacking from the more comprehensive databases. Therefore, we determined the intra- and inter-individual components of variation in healthy subjects. These data were used to define desirable goals for imprecision, bias and total error, indices of individuality and reference change values. METHODS Plasma samples were collected...

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Biological variation of vitamins in blood of healthy individuals.

BACKGROUND Components of biological variation can be used to define objective quality specifications (imprecision, bias, and total error), to assess the usefulness of reference values [index of individuality (II)], and to evaluate significance of changes in serial results from an individual [reference change value (RCV)]. However, biological variation data on vitamins in blood are limited. The ...

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ژورنال

عنوان ژورنال: Clinical Chemistry and Laboratory Medicine

سال: 2010

ISSN: 1437-4331,1434-6621

DOI: 10.1515/cclm.2010.008